Disease: Senile Plaques
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TAS2R62P taste 2 receptor member 62 pseudogene 0.729 0.192
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
NRGN Q92686 neurogranin 0.48 0.608 0.615
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
LRP8 Q14114 LDL receptor related protein 8 1.00 0.644 0.346
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885